Despite not officially beginning an affair with Brenda from Young Sheldon, George's interactions could lead to his divorce. Fans of The Big Bang Theory are aware that Sheldon's dad will cheat on his mom, starting in the season 4 finale. Season 5 hinted at the affair when George and Brenda spent time together at a bar. Although nothing happened beyond flirting, it could be the beginning of George's infidelity. This storyline may impact Sheldon's character development in both Young Sheldon and The Big Bang Theory.